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Histology

VPS has a team of highly trained histologists and a fully equipped and state of the art GLP-compliant histology laboratory. We offer our clients the experience, expertise, and capacity to process standardized and specialized tissue samples, from the smallest of studies to carcinogenicity studies. Our capabilities include routine histological procedures such as trimming of fixed tissues, processing of standard as well as oversized specimens, paraffin and plastic embedding, microtomy, Hematoxylin and Eosin (H&E) staining, and many special staining techniques.

Our Laboratory Director has over 30 years of experience in managing a GLP-compliant histology laboratory. Our laboratory staff, which includes senior histologists, histology technicians, and research associates, provides expert study set-up, tissue handling, specimen preparation, and Quality Control for a wide variety of studies, tissues, and species.

In addition to standard, specialized, and/or oversized paraffin histology, we offer the following GLP-compliant plastics histology services as well:

  • Glycol Methyl Methacrylate (GMA), which is often used to process delicate structures that are difficult to section in paraffin. Our laboratory is equipped with 2 complete GMA processing and microtomy stations.
  • Technovit 7200 VLC, which is often used to process undecalcified and/or specimens containing metal or ceramic implants. Our laboratory is equipped with 3 complete Exakt™ Systems which, along with specialized dehydration and resin (Technovit 7200) infiltration, allow our experienced technicians to process, section, grind, and polish tissue sections that contain:
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    o   Metals (Titanium, Nitinol, etc.) 
    o   Ceramics
    o   Polymers
    o   Undecalcified Bone
    o   Bone Cements
    o   Void Fillers

Faxitron X-ray
VPS offers high resolution radiographs of excised tissue with the Faxitron MX-20 self-contained cabinet x-ray system.

High resolution Faxitron radiographs are used in our laboratory to aide in assessing bone healing and the placement of implants prior to trimming and preparing specimens for processing.

Slide Scanning
VPS offers microscopic slide scanning using Motic’s digital slide scanning system. This system combines a motorized microscope platform with slide scanning and control software, and it allows us to scan a variety of types and sizes of slides using various objectives (magnifications). The resulting high-resolution digital scans of the tissue sections can then be saved on electronic media and/or annotated and integrated in the pathology report.